CHMP2A antibody (AA 1-222)
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- Target See all CHMP2A Antibodies
- CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
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Binding Specificity
- AA 1-222
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHMP2A antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Charged multivesicular body protein 2a protein (1-222AA)
- Isotype
- IgG
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anti-Charged Multivesicular Body Protein 2A (CHMP2A) (Internal Region) antibody
CHMP2A Reactivity: Human, Rat, Mouse WB, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (AA 1-100) antibodyCHMP2A Reactivity: Rat WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2A (CHMP2A) antibody (HRP)CHMP2A Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Rabbit Polyclonal HRP
anti-Charged Multivesicular Body Protein 2A (CHMP2A) antibody (FITC)CHMP2A Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Rabbit Polyclonal FITC
anti-Charged Multivesicular Body Protein 2A (CHMP2A) antibody (Biotin)CHMP2A Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Rabbit Polyclonal Biotin
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (AA 1-222) antibodyCHMP2A Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (C-Term) antibodyCHMP2A Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Bat, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (N-Term) antibodyCHMP2A Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio), Bat, Monkey, Chicken, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
- Alternative Name
- CHMP2A (CHMP2A Products)
- Synonyms
- BC-2 antibody, BC2 antibody, CHMP2 antibody, VPS2 antibody, VPS2A antibody, 1500016L11Rik antibody, RGD1305050 antibody, bc-2 antibody, bc2 antibody, chmp2 antibody, vps2 antibody, vps2a antibody, fj10d05 antibody, wu:fi18h03 antibody, wu:fj10d05 antibody, zgc:55361 antibody, charged multivesicular body protein 2a antibody, charged multivesicular body protein 2A antibody, Charged multivesicular body protein 2a antibody, charged multivesicular body protein 2A L homeolog antibody, ATEG_06167 antibody, LOC5570080 antibody, EDI_289610 antibody, PTRG_09933 antibody, NAEGRDRAFT_39042 antibody, PITG_17335 antibody, Tsp_00033 antibody, LOC100284170 antibody, LOC100284688 antibody, chm2a antibody, chmp2a antibody, CHMP2A antibody, Chmp2a antibody, chmp2a.L antibody
- Background
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Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis (PubMed:21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed:26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
Aliases: BC 2 antibody, BC2 antibody, Charged multivesicular body protein 2a antibody, CHM2A_HUMAN antibody, CHMP2 antibody, CHMP2a antibody, Chromatin modifying protein 2a antibody, Chromatin-modifying protein 2a antibody, hVps2 1 antibody, hVps2-1 antibody, putative breast adenocarcinoma marker antibody, Putative breast adenocarcinoma marker BC-2 antibody, Putative breast adenocarcinoma marker BC2 antibody, Vacuolar protein sorting associated protein 2 1 antibody, Vacuolar protein sorting-associated protein 2-1 antibody, Vps2 1 antibody, VPS2 antibody, Vps2-1 antibody, VPS2A antibody
- UniProt
- O43633
- Pathways
- SARS-CoV-2 Protein Interactome
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