MACROD1 antibody (AA 83-325)
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- Target See all MACROD1 products
- MACROD1 (MACRO Domain Containing 1 (MACROD1))
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Binding Specificity
- AA 83-325
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MACROD1 antibody is un-conjugated
- Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA)
- Isotype
- IgG
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anti-MACRO Domain Containing 1 (MACROD1) (AA 83-132) antibody
MACROD1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-MACRO Domain Containing 1 (MACROD1) (N-Term) antibodyMACROD1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MACROD1 (MACRO Domain Containing 1 (MACROD1))
- Alternative Name
- MACROD1 (MACROD1 Products)
- Synonyms
- lrp16 antibody, d930010j01rik antibody, LRP16 antibody, AI604841 antibody, AW743046 antibody, D930010J01Rik antibody, Lrp16 antibody, MACRO domain containing 1 antibody, MACRO domain containing 1 L homeolog antibody, MACROD1 antibody, macrod1 antibody, macrod1.L antibody, Macrod1 antibody
- Background
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Background: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.
Aliases: MACROD1 antibody, LRP16 antibody, ADP-ribose glycohydrolase MACROD1 antibody, MACRO domain-containing protein 1 antibody, O-acetyl-ADP-ribose deacetylase MACROD1 antibody, EC 3.1.1.106 antibody, Protein LRP16 antibody, [Protein ADP-ribosylaspartate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody, [Protein ADP-ribosylglutamate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody
- UniProt
- Q9BQ69
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