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TBK1 antibody (AA 150-181)

TBK1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB16573 unconjugated
Catalog No. ABIN392371
  • Target See all TBK1 Antibodies
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    Binding Specificity
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-181
    Reactivity
    • 70
    • 48
    • 28
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 73
    • 11
    • 1
    Rabbit
    Clonality
    • 70
    • 15
    Polyclonal
    Conjugate
    • 45
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TBK1 antibody is un-conjugated
    Application
    • 58
    • 42
    • 25
    • 10
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    Zf, X
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TBK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-181 amino acids from human TBK.
    Clone
    RB16573
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:2000. WB: 1:2000. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Jiang, Song, Li, Xue, Deng, Li, Liu, Wang: "Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells." in: Mediators of inflammation, Vol. 2017, pp. 9891673, (2018) (PubMed).

  • Target
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    Alternative Name
    TBK1 (TBK1 Products)
    Synonyms
    nak antibody, t2k antibody, TBK1 antibody, wu:fk70c05 antibody, zgc:136548 antibody, NAK antibody, T2K antibody, 1200008B05Rik antibody, AI462036 antibody, AW048562 antibody, TANK binding kinase 1 L homeolog antibody, TANK binding kinase 1 antibody, TANK-binding kinase 1 antibody, tbk1.L antibody, TBK1 antibody, tbk1 antibody, Tbk1 antibody
    Background
    The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TKB is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.
    Molecular Weight
    83642
    Gene ID
    29110
    NCBI Accession
    NP_037386
    UniProt
    Q9UHD2
    Pathways
    TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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