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Metabotropic Glutamate Receptor 5 antibody (AA 458-580)

GRM5 Reactivity: Human WB, IHC, ELISA, ICC, FACS, Neut Host: Mouse Monoclonal 1A11D10 unconjugated
Catalog No. ABIN5611178
  • Target See all Metabotropic Glutamate Receptor 5 (GRM5) Antibodies
    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
    Binding Specificity
    • 41
    • 33
    • 16
    • 15
    • 13
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 458-580
    Reactivity
    • 112
    • 85
    • 83
    • 11
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 91
    • 45
    • 2
    • 2
    • 1
    Mouse
    Clonality
    • 88
    • 53
    Monoclonal
    Conjugate
    • 43
    • 10
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
    Application
    • 119
    • 57
    • 41
    • 36
    • 30
    • 28
    • 19
    • 18
    • 13
    • 13
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human GRM5 (AA: extra 458-580) expressed in E. coli.
    Clone
    1A11D10
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: N/A, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
    Alternative Name
    GRM5 (GRM5 Products)
    Background

    Description: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.

    Aliases: mGlu5, GPRC1E, MGLUR5, PPP1R86

    Molecular Weight
    132.5 kDa
    Gene ID
    2915
    HGNC
    2915
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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