GRM8 antibody (AA 440-583)
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- Target See all GRM8 Antibodies
- GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
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Binding Specificity
- AA 440-583
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GRM8 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human GRM8 (AA: extra 440-583) expressed in E. coli.
- Clone
- 4C1C1
- Isotype
- IgG1
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anti-Glutamate Receptor, Metabotropic 8 (GRM8) antibody
GRM8 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (N-Term) antibodyGRM8 Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Horse, Bat, Chicken, Dog, Hamster, Sheep IHC, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (C-Term) antibodyGRM8 Reactivity: Human, Mouse, Rat, Monkey, Horse, Bat IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 486-575) antibodyGRM8 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4A7 unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 486-575) antibodyGRM8 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) antibodyGRM8 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (C-Term) antibodyGRM8 Reactivity: Human, Mouse, Rat, Monkey, Horse, Chimpanzee IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 841-890) antibodyGRM8 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (Extracellular Domain), (N-Term) antibodyGRM8 Reactivity: Human IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 365-377), (Extracellular), (N-Term) antibodyGRM8 Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
- Alternative Name
- GRM8 (GRM8 Products)
- Synonyms
- mGluR8 antibody, GRM8 antibody, MGLUR8 antibody, GLUR8 antibody, GPRC1H antibody, mGlu8 antibody, A230002O04 antibody, Gprc1h antibody, Glur8 antibody, Mglur8 antibody, mGluR8b antibody, mGlur antibody, glutamate metabotropic receptor 8 antibody, metabotropic glutamate receptor 8 antibody, glutamate receptor, metabotropic 8 antibody, GRM8 antibody, MGLUR8 antibody, LOAG_14062 antibody, Grm8 antibody
- Background
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Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Aliases: GLUR8, mGlu8, GPRC1H, MGLUR8
- Molecular Weight
- 101.7 kDa
- Gene ID
- 2918
- HGNC
- 2918
- Pathways
- cAMP Metabolic Process, Synaptic Membrane
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