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Phospholipase C gamma 2 antibody (pTyr753)

PLCG2 Reactivity: Human, Rat, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256017
  • Target See all Phospholipase C gamma 2 (PLCG2) Antibodies
    Phospholipase C gamma 2 (PLCG2)
    Binding Specificity
    • 31
    • 22
    • 16
    • 15
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr753
    Reactivity
    • 130
    • 66
    • 52
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Human, Rat, Mouse
    Host
    • 124
    • 6
    Rabbit
    Clonality
    • 120
    • 10
    Polyclonal
    Conjugate
    • 59
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Phospholipase C gamma 2 antibody is un-conjugated
    Application
    • 95
    • 40
    • 40
    • 36
    • 34
    • 22
    • 19
    • 17
    • 11
    • 7
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Phospho-PLCG2 (Tyr753) Antibody detects endogenous levels of PLCG2 only when phosphorylated at Tyrosine 753.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human PLCG2 around the phosphorylation site of Tyr753.
    Isotype
    IgG
    Top Product
    Discover our top product PLCG2 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Phospholipase C gamma 2 (PLCG2)
    Alternative Name
    PLCG2 (PLCG2 Products)
    Synonyms
    PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
    Background

    Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

    Gene: PLCG2

    Molecular Weight
    150kDa
    Gene ID
    5336
    UniProt
    P16885
    Pathways
    RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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