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CYP2S1 antibody (C-Term)

CYP2S1 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB17020 unconjugated
Catalog No. ABIN656566
  • Target See all CYP2S1 Antibodies
    CYP2S1 (Cytochrome P450, Family 2, Subfamily S, Polypeptide 1 (CYP2S1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 399-428, C-Term
    Reactivity
    • 38
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 39
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP2S1 antibody is un-conjugated
    Application
    • 38
    • 21
    • 20
    • 19
    • 13
    • 13
    • 7
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CYP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human CYP2S1.
    Clone
    RB17020
    Isotype
    Ig Fraction
  • Application Notes
    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Yang, Zhou, Li, Tong, Sun, Qing, Sun, Yang, Hu, Jiang, Yan, He, Wan: "Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines." in: Scientific reports, Vol. 6, pp. 33078, (2016) (PubMed).

    Yang, Li, Li, Tong, Hu, Yang, Yan, He, Wan: "CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of ?-catenin signaling." in: Experimental cell research, Vol. 331, Issue 2, pp. 377-86, (2015) (PubMed).

  • Target
    CYP2S1 (Cytochrome P450, Family 2, Subfamily S, Polypeptide 1 (CYP2S1))
    Alternative Name
    CYP2S1 (CYP2S1 Products)
    Synonyms
    1200011C15Rik antibody, AU041727 antibody, C79779 antibody, cytochrome P450, family 2, subfamily s, polypeptide 1 antibody, cytochrome P450 family 2 subfamily S member 1 antibody, Cyp2s1 antibody, CYP2S1 antibody
    Background
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens, however, the specific function of the human protein has not been determined.
    Molecular Weight
    55817
    Gene ID
    29785
    NCBI Accession
    NP_085125
    UniProt
    Q96SQ9
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