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SAV1 antibody

SAV1 Reactivity: Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7075505
  • Target See all SAV1 Antibodies
    SAV1 (Salvador Homolog 1 (SAV1))
    Reactivity
    • 31
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 24
    • 6
    • 1
    Rabbit
    Clonality
    • 28
    • 3
    Polyclonal
    Conjugate
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    This SAV1 antibody is un-conjugated
    Application
    • 29
    • 19
    • 6
    • 4
    • 4
    • 2
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse SAV1
    Top Product
    Discover our top product SAV1 Primary Antibody
  • Application Notes
    IHC/IF (M,R) 1:200-1:1400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    SAV1 (Salvador Homolog 1 (SAV1))
    Alternative Name
    SAV1 (SAV1 Products)
    Synonyms
    SAV antibody, WW45 antibody, WWP4 antibody, 1700040G09Rik antibody, Salv antibody, Sav antibody, Wwp3 antibody, Wwp4 antibody, salvador family WW domain containing protein 1 antibody, salvador family WW domain containing 1 antibody, SAV1 antibody, Sav1 antibody
    Background
    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
    Gene ID
    64010
    NCBI Accession
    NP_071311
    UniProt
    Q8VEB2
    Pathways
    Stem Cell Maintenance
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