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Cadherin 4 antibody (Middle Region)

CDH4 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782140
  • Target See all Cadherin 4 (CDH4) Antibodies
    Cadherin 4 (CDH4)
    Binding Specificity
    • 15
    • 10
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 59
    • 5
    • 1
    Rabbit
    Clonality
    • 61
    • 4
    Polyclonal
    Conjugate
    • 24
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cadherin 4 antibody is un-conjugated
    Application
    • 54
    • 25
    • 21
    • 19
    • 14
    • 13
    • 13
    • 10
    • 9
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RIISGDPSGH FSVRTDPVTN EGMVTVVKAV DYELNRAFML TVMVSNQAPL
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 77%
    Characteristics
    This is a rabbit polyclonal antibody against CDH4. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CDH4
    Top Product
    Discover our top product CDH4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 916 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Cadherin 4 (CDH4)
    Alternative Name
    CDH4 (CDH4 Products)
    Synonyms
    cad4 antibody, rcad antibody, R-cadherin antibody, cadherin-4 antibody, AW120700 antibody, R-Cadh antibody, Rcad antibody, Cdh4l antibody, zgc:136316 antibody, CAD4 antibody, RCAD antibody, cadherin 4 antibody, cadherin 4, type 1, R-cadherin (retinal) antibody, Cadherin-4 antibody, cdh4 antibody, Cdh4 antibody, CDH4 antibody, cdh-4 antibody
    Background
    CDH4 gene is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
    Alias Symbols: CAD4, FLJ22202, FLJ40547, MGC126700, MGC138355, RCAD
    Protein Interaction Partner: FUS, Dlg4, CDK5RAP3, CDH2,
    Protein Size: 916
    Molecular Weight
    82 kDa
    Gene ID
    1002
    NCBI Accession
    NM_001794, NP_001785
    UniProt
    P55283
    Pathways
    Cell-Cell Junction Organization, Regulation of Cell Size
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