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HFE antibody (AA 115-205)

HFE Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1G12 unconjugated
Catalog No. ABIN561252
  • Target See all HFE Antibodies
    HFE (Hemochromatosis (HFE))
    Binding Specificity
    • 16
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 115-205
    Reactivity
    • 46
    • 9
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 5
    Mouse
    Clonality
    • 44
    • 3
    Monoclonal
    Conjugate
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HFE antibody is un-conjugated
    Application
    • 41
    • 20
    • 14
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant HFE.
    Sequence
    SHTLQVILGC EMQEDNSTEG YWKYGYDGQD HLEFCPDTLD WRAAEPRAWP TKLEWERHKI RARQNRAYLE RDCPAQLQQL LELGRGVLDQ Q
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    HFE (NP_000401, 115 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1G12
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Lenarduzzi, Hui, Yue, Ito, Shi, Williams, Bruce, Sakemura-Nakatsugawa, Xu, Schimmer, Liu: "Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer." in: PLoS ONE, Vol. 8, Issue 8, pp. e74075, (2013) (PubMed).

  • Target
    HFE (Hemochromatosis (HFE))
    Alternative Name
    HFE (HFE Products)
    Synonyms
    HFE1 antibody, HH antibody, HLA-H antibody, MVCD7 antibody, TFQTL2 antibody, MR2 antibody, hemochromatosis antibody, HFE antibody, Hfe antibody
    Background
    Full Gene Name: hemochromatosis
    Synonyms: HFE1,HH,HLA-H,MGC103790,dJ221C16.10.1
    Gene ID
    3077
    NCBI Accession
    NM_000410
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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