For best experience we recommend to activate Javascript in your browser.

E2F6 antibody (Internal Region)

Name: E2F6 antibody (Internal Region)
SKU: ABIN6261413
Price: 390.77 USD
Availability: InStock

E2F6 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

Western blot analysis of extracts from Mouse muscle, using E2F6 Antibody.

IF/ICC

Western blot analysis on HepG2 cell lysate using E2F6 Antibody,The lane on the left is treated with the antigen-specific peptide.

ABIN6266532 at 1/100 staining human brain tissue sections by IHC-P.

IHC

4 images

(1 reference)

Catalog No. ABIN6261413

Datasheet as PDF

Target See all E2F6 Antibodies

E2F6 (E2F Transcription Factor 6 (E2F6))
Binding Specificity
5

3

2

2

2

1

1

1

1

1

1

1

1
Internal Region
Reactivity
37

22

17

6

5

5

5

4

3

1

1
Human, Mouse, Rat
Host
30

6

1
Rabbit
Compatible Secondaries
Clonality
32

5
Polyclonal
Conjugate
30

1

1

1

1

1

1

1
This E2F6 antibody is un-conjugated
Application
28

11

11

8

5

5

3

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity

E2F6 Antibody detects endogenous levels of total E2F6.

Predicted Reactivity

Pig,Bovine,Horse,Sheep,Dog

Purification

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen

A synthesized peptide derived from human E2F6, corresponding to a region within the internal amino acids.

Isotype

IgG
anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibody
E2F6 Reactivity: Human WB, IF, IP, ChIP Host: Rabbit Polyclonal unconjugated

anti-E2F Transcription Factor 6 (E2F6) antibody
E2F6 Reactivity: Human WB, IHC, IF, IP, ChIP Host: Rabbit Polyclonal unconjugated

anti-E2F Transcription Factor 6 (E2F6) antibody
E2F6 Reactivity: Human, Mouse WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibody
E2F6 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1F7-A9 unconjugated

anti-E2F Transcription Factor 6 (E2F6) antibody
E2F6 Reactivity: Human, Mouse WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated

anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibody
E2F6 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-E2F Transcription Factor 6 (E2F6) (Internal Region) antibody
E2F6 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibody
E2F6 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-E2F Transcription Factor 6 (E2F6) (AA 43-92) antibody
E2F6 Reactivity: Human, Mouse, Pig, Dog, Guinea Pig, Horse, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-E2F Transcription Factor 6 (E2F6) (Center) antibody
E2F6 Reactivity: Human, Mouse, Rat, Pig, Cow WB, IHC, ChIP Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date

12 months
Ai, Zhang, Gao, Qin, Zhong, Gu, Li, Qiao, Tian, Cui, Yang, Bi, Xiao, Chen, Liu, Zhou, Sun, Yang: "Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition." in: Oncotarget, Vol. 8, Issue 41, pp. 70192-70203, (2018) (PubMed).
Target

E2F6 (E2F Transcription Factor 6 (E2F6))

Alternative Name

E2F6 (E2F6 Products)

Synonyms

E2F-6 antibody, AI462434 antibody, E2F6b antibody, EMA antibody, E2F transcription factor 6 antibody, E2F6 antibody, E2f6 antibody

Background

Description: Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.
Gene: E2F6

Molecular Weight

31kDa

Gene ID

1876

UniProt

O75461