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HMGCS2 antibody

HMGCS2 Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7257752
  • Target See all HMGCS2 Antibodies
    HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))
    Reactivity
    • 31
    • 8
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 28
    • 2
    • 1
    Rabbit
    Clonality
    • 30
    • 1
    Polyclonal
    Conjugate
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HMGCS2 antibody is un-conjugated
    Application
    • 20
    • 10
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human HMGCS2 (NP_005509.1).
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))
    Alternative Name
    HMGCS2 (HMGCS2 Products)
    Synonyms
    1300002P16 antibody, mHS antibody, DDBDRAFT_0219349 antibody, DDBDRAFT_0219924 antibody, DDB_0219349 antibody, DDB_0219924 antibody, Hmgcs1 antibody, Mt3h3mg antibody, hmgCoA antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 2 antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 antibody, hydroxymethylglutaryl-CoA synthase antibody, hydroxymethylglutaryl-coa synthase antibody, 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 antibody, HMGCS2 antibody, Hmgcs2 antibody, mvaS antibody, CNC05080 antibody, HMCS1 antibody, hgsA antibody, MFER_RS00425 antibody, LOC100285783 antibody, ECU10_0510 antibody, Eint_100450 antibody
    Background
    The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 50 kDa

    Calculated_MW: 50 kDa/52 kDa/56 kDa

    Gene ID
    3158
    UniProt
    P54868
    Pathways
    Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha
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