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CENPT antibody (Internal Region)

CENPT Reactivity: Human, Mouse WB, ELISA, ICC, IF, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258439
  • Target See all CENPT Antibodies
    CENPT (Centromere Protein T (CENPT))
    Binding Specificity
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 22
    • 16
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 36
    • 1
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CENPT antibody is un-conjugated
    Application
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Specificity
    CENPT Antibody detects endogenous levels of total CENPT.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CENPT, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    CENPT (Centromere Protein T (CENPT))
    Alternative Name
    CENPT (CENPT Products)
    Synonyms
    cenp-t antibody, MGC145722 antibody, CENP-T antibody, wu:fc31h11 antibody, wu:fc75c05 antibody, C16orf56 antibody, G630055P03Rik antibody, RGD1309383 antibody, centromere protein T antibody, centromere protein T L homeolog antibody, si:ch211-225g23.1 antibody, cenpt antibody, cenpt.L antibody, CENPT antibody, si:ch211-225g23.1 antibody, Cenpt antibody
    Background

    Description: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.

    Gene: CENPT

    Molecular Weight
    65 kDa
    Gene ID
    80152
    UniProt
    Q96BT3
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