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Hepsin antibody (AA 294-413)

HPN Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7168912
  • Target See all Hepsin (HPN) Antibodies
    Hepsin (HPN)
    Binding Specificity
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 294-413
    Reactivity
    • 45
    • 16
    • 16
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 2
    • 1
    Rabbit
    Clonality
    • 43
    • 2
    Polyclonal
    Conjugate
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Hepsin antibody is un-conjugated
    Application
    • 32
    • 14
    • 13
    • 13
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Serine protease hepsin protein (294-413AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Hepsin (HPN)
    Alternative Name
    HPN (HPN Products)
    Synonyms
    TMPRSS1 antibody, Hlb320 antibody, hepsin antibody, si:dkey-33i11.3 antibody, HPN antibody, si:dkey-33i11.3 antibody, Hpn antibody
    Background

    Background: Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL (PubMed:21875933, PubMed:15839837). Plays a role in cell growth and maintenance of cell morphology (PubMed:8346233, PubMed:21875933). Plays a role in the proteolytic processing of ACE2 (PubMed:24227843). Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization (PubMed:26673890).

    Aliases: EC 3.4.21. antibody, HEPS antibody, HEPS_HUMAN antibody, Hepsin antibody, Hpn antibody, Serine protease hepsin antibody, Serine protease hepsin catalytic chain antibody, Serine protease hepsin non catalytic chain antibody, TMPRSS 1 antibody, TMPRSS1 antibody, Transmembrane protease serine 1 antibody

    UniProt
    P05981
    Pathways
    Regulation of Hormone Metabolic Process, Sensory Perception of Sound
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