Survivin antibody (AA 85-142)
(1 reference)-
- Target See all Survivin (BIRC5) Antibodies
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
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Binding Specificity
- AA 85-142
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Survivin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Pig,Horse,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Survivin
- Isotype
- IgG
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anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-100) antibody
BIRC5 Reactivity: Human WB, ELISA, IF, IP, RNAi Host: Mouse Monoclonal 5B10 unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 Reactivity: Human WB, IHC, ICC, IP Host: Mouse Monoclonal 1# unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (pThr117) antibodyBIRC5 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) antibodyBIRC5 Reactivity: Human WB, ELISA, IHC, ICC, FACS Host: Mouse Monoclonal 1H5 unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (C-Term) antibodyBIRC5 Reactivity: Human WB, IF, IHC (p), ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 Reactivity: Human WB, IF, PLA Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) antibodyBIRC5 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 5 (BIRC5) antibodyBIRC5 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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: "Survivin as a Novel Biomarker in the Pathogenesis of Acne Vulgaris and Its Correlation to Insulin-Like Growth Factor-I." in: Disease markers, Vol. 2016, pp. 7040312, (2017) (PubMed).
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: "Survivin as a Novel Biomarker in the Pathogenesis of Acne Vulgaris and Its Correlation to Insulin-Like Growth Factor-I." in: Disease markers, Vol. 2016, pp. 7040312, (2017) (PubMed).
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- Target
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- Alternative Name
- Survivin (BIRC5 Products)
- Synonyms
- AP14 antibody, API4 antibody, EPR-1 antibody, AAC-11 antibody, Api4 antibody, TIAP antibody, survivin40 antibody, bir5a antibody, survivin antibody, BIR1 antibody, Su2 antibody, XBIR1 antibody, XSurvivin1 antibody, Xsvv1 antibody, api4 antibody, bir1-A antibody, epr-1 antibody, svv1 antibody, xSurvivin antibody, xsurv antibody, Su1 antibody, birc5.2 antibody, svv2 antibody, xSurvivin2 antibody, bir5b antibody, SIX antibody, birc5.2-a antibody, birc5.2-b antibody, baculoviral IAP repeat containing 5 antibody, baculoviral IAP repeat-containing 5 antibody, baculoviral IAP repeat containing 5a antibody, baculoviral IAP repeat-containing 5, gene 1 L homeolog antibody, baculoviral IAP repeat containing 5 L homeolog antibody, baculoviral IAP repeat containing 5b antibody, baculoviral IAP repeat containing 5 S homeolog antibody, BIRC5 antibody, Birc5 antibody, birc5a antibody, birc5.1.L antibody, birc5.2.L antibody, birc5b antibody, birc5.2.S antibody
- Background
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Synonyms: API4, EPR-1, Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, BIRC5, IAP4
Background: Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex, directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7. Isoform 2 and isoform 3 do not appear to play vital roles in mitosis. Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform.
- Gene ID
- 332
- UniProt
- O15392
- Pathways
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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