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APLP1 antibody (AA 39-300)

APLP1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6136993
  • Target See all APLP1 Antibodies
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    Binding Specificity
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-300
    Reactivity
    • 34
    • 31
    • 16
    • 6
    • 5
    • 2
    • 1
    Human
    Host
    • 44
    • 2
    Rabbit
    Clonality
    • 45
    • 1
    Polyclonal
    Conjugate
    • 13
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APLP1 antibody is un-conjugated
    Application
    • 32
    • 13
    • 13
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    SLAGGSPGAA EAPGSAQVAG LCGRLTLHRD LRTGRWEPDP QRSRRCLRDP QRVLEYCRQM YPELQIARVE QATQAIPMER WCGGSRSGSC AHPHHQVVPF RCLPGEFVSE ALLVPEGCRF LHQERMDQCE SSTRRHQEAQ EACSSQGLIL HGSGMLLPCG SDRFRGVEYV CCPPPGTPDP SGTAVGDPST RSWPPGSRVE GAEDEEEEES FPQPVDDYFV EPPQAEEEEE TVPPPSSHTL AVVGKVTPTP RPTDGVDIYF GM
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 39-300 of human APLP1 (NP_005157.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:10 - 1:100
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    Alternative Name
    APLP1 (APLP1 Products)
    Synonyms
    aplp antibody, MGC115336 antibody, APLP antibody, Aplp1_retired antibody, RGD1561211 antibody, amyloid beta precursor like protein 1 antibody, amyloid beta precursor like protein 1 L homeolog antibody, amyloid beta (A4) precursor-like protein 1 antibody, APLP1 antibody, aplp1.L antibody, aplp1 antibody, Aplp1 antibody
    Background
    This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.,APLP1,APLP,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,APLP1
    Molecular Weight
    72 kDa
    Gene ID
    333
    UniProt
    P51693
    Pathways
    cAMP Metabolic Process
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