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NOS2 antibody (AA 14-100)

Name: NOS2 antibody (AA 14-100)
SKU: ABIN677228
Price: 384.62 USD
Availability: InStock

NOS2 Reactivity: Human, Mouse, Rat, Chicken WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

Formalin-fixed and paraffin-embedded : rat brain labeled with Rabbit Anti-NOS-2/iNOS Polyclonal Antibody, Unconjugated (ABIN677228) 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-NOS-2/iNOS Polyclonal Antibody, Unconjugated (ABIN677228) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, FITC conjugated used at 1:200 dilution for 40 minutes at 37°C and DAPI

Formalin-fixed and paraffin embedded human kidney labeled with Anti-NOS-2/iNOS Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining.

IHC (p)

Formalin-fixed and paraffin embedded rat lung labeled with Anti-NOS-2/iNOS Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining.

IHC (p)

Paraformaldehyde-fixed, paraffin embedded rat liver, Antigen retrieval by boiling in sodium citrate buffer (pH6.

IHC (p)

5 images

(10 references)

Catalog No. ABIN677228

Datasheet as PDF

Target See all NOS2 Antibodies

NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
Binding Specificity
16

15

12

10

8

6

6

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 14-100
Reactivity
109

68

68

16

2

1
Human, Mouse, Rat, Chicken
Host
126

10
Rabbit
Compatible Secondaries
Clonality
118

18
Polyclonal
Conjugate
68

16

8

6

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2
This NOS2 antibody is un-conjugated
Application
109

44

34

31

26

25

23

17

17

14

7

4

2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Chicken, Human, Mouse, Rat

Predicted Reactivity

Dog,Pig,Rabbit,Guinea Pig

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from mouse NOS-2

Isotype

IgG
anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibody
NOS2 Reactivity: Human, Mouse WB, IHC, ELISA, FACS Host: Mouse Monoclonal 4-00E-05 unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 43-213) antibody
NOS2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 518-694) antibody
NOS2 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 830-860) antibody
NOS2 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB18210 unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (C-Term) antibody
NOS2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (Thr177) antibody
NOS2 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 533-696) antibody
NOS2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 533-696) antibody
NOS2 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C6 unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibody
NOS2 Reactivity: Human, Mouse, Rat, Chicken, Dog WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 734-966) antibody
NOS2 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C1 unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Liu, Li, Yang, Niu, Zhao, Zhao, Wang: "Valproic acid attenuates inflammation of optic nerve and apoptosis of retinal ganglion cells in a rat model of optic neuritis." in: Biomedicine & pharmacotherapy, Vol. 96, pp. 1363-1370, (2018) (PubMed).

Zhao, Jiang, Wang, Geng, Wang, Han, Wang: "The Roles of Reactive Oxygen Species and Nitric Oxide in Perfluorooctanoic Acid-Induced Developmental Cardiotoxicity and l-Carnitine Mediated Protection." in: International journal of molecular sciences, Vol. 18, Issue 6, (2017) (PubMed).

Sun, Yang, Zhang, Zhao: "Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats." in: Experimental animals, (2017) (PubMed).

Xiong, Wang, Chu, Chen, Guo: "Salvianolic Acid B Restored Impaired Barrier Function via Downregulation of MLCK by microRNA-1 in Rat Colitis Model." in: Frontiers in pharmacology, Vol. 7, pp. 134, (2016) (PubMed).

Bai, Zhang, Li, Liu, Lou, Ma, Luo, Ren: "Somatostatin prevents lipopolysaccharide?induced neurodegeneration in the rat substantia nigra by inhibiting the activation of microglia." in: Molecular medicine reports, Vol. 12, Issue 1, pp. 1002-8, (2015) (PubMed).

Sun, Zhang, Guan, Zhou, Sun: "Alpha-lipoic acid attenuates trinitrobenzene sulfonic acid-induced ulcerative colitis in mice." in: International journal of clinical and experimental medicine, Vol. 8, Issue 1, pp. 358-67, (2015) (PubMed).

Wang, Fang, Hu, Li, Hong: "Seawater immersion aggravates sciatic nerve injury in rats." in: Experimental and therapeutic medicine, Vol. 9, Issue 4, pp. 1153-1160, (2015) (PubMed).

Pei, Wang et al.: "Propofol attenuates LPS-induced tumor necrosis factor-?, interleukin-6 and nitric oxide expression in canine peripheral blood mononuclear cells possibly through down-regulation of nuclear factor ..." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, (2014) (PubMed).

Karadeniz, Cavuso?lu, Turkmen, Uyan?kgil, Karadeniz, Akdemir, Tuglu, Ates, Erbas: "Experimental comparison of protective characteristics of enalapril and trimetazidine in diabetic nephropathy." in: Renal failure, Vol. 36, Issue 8, pp. 1283-90, (2014) (PubMed).
Target

NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Alternative Name

iNOS (NOS2 Products)

Synonyms

HEP-NOS antibody, INOS antibody, NOS antibody, NOS2A antibody, NOS-II antibody, Nos-2 antibody, Nos2a antibody, i-NOS antibody, iNOS antibody, iNos antibody, NOS2a antibody, NOS2 antibody, BmNOS2 antibody, Nsl antibody, nos2 antibody, nitric oxide synthase 2 antibody, nitric oxide synthase 2, inducible antibody, inducible nitric oxide synthase antibody, inducible nitric-oxide synthase antibody, nanos C2HC-type zinc finger 2 antibody, NOS2 antibody, Nos2 antibody, nos2 antibody, LOC396821 antibody, NANOS2 antibody

Background

Synonyms: iNOS, Nos-2, Nos2a, i-NOS, NOS-II, Nitric oxide synthase, inducible, Inducible NO synthase, Inducible NOS, Macrophage NOS, MAC-NOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, Nos2, Inosl
Background: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.

Gene ID

18126

UniProt

P29477

Pathways

Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process