IFNGR1 Protein (AA 18-245) (Fc Tag)
-
- Target See all IFNGR1 Proteins
- IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 18-245
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IFNGR1 protein is labelled with Fc Tag.
- Purpose
- Human IFN gamma R1/IFNGR1 Protein
- Sequence
- Glu18-Gly245
- Characteristics
- Recombinant Human IFN gamma R1/IFNGR1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu18-Gly245.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human Human IFN gamma, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 13.0ng/ml determined by ELISA. See testing image for detail.
-
Interferon gamma Receptor 1 (IFNGR1) protein (His tag)
IFNGR1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interferon gamma Receptor 1 (IFNGR1) protein (Fc Tag)IFNGR1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interferon gamma Receptor 1 (IFNGR1) (Active) protein (His tag)IFNGR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Interferon gamma Receptor 1 (IFNGR1) (Active) protein (Fc Tag)IFNGR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interferon gamma Receptor 1 (IFNGR1) (AA 267-489) protein (His tag)Crystallography grade IFNGR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 18-245) protein (His tag)Crystallography grade IFNGR1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 26-254) protein (His tag)Crystallography grade IFNGR1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 276-477) protein (His tag)Crystallography grade IFNGR1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 18-489) protein (rho-1D4 tag)Crystallography grade IFNGR1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 26-477) protein (rho-1D4 tag)Crystallography grade IFNGR1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
- Alternative Name
- IFN gamma R1 (IFNGR1 Products)
- Synonyms
- CD119 Protein, IFNGR Protein, IFN-gammaR Protein, Ifgr Protein, Ifngr Protein, Nktar Protein, IFNGR1 Protein, MGC129098 Protein, ifngr1 Protein, MGC194858 Protein, MGC194873 Protein, zgc:194858 Protein, cd119 Protein, ifngr Protein, DKFZp469K1232 Protein, interferon gamma receptor 1 Protein, cytokine receptor family member B17 Protein, IFNGR1 Protein, Ifngr1 Protein, crfb17 Protein, ifngr1 Protein
- Background
- IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.
- Molecular Weight
- 52.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.
- Pathways
- Interferon-gamma Pathway
-
