Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

APRT antibody (N-Term)

APRT Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB20509 unconjugated
Catalog No. ABIN389426
  • Target See all APRT Antibodies
    APRT (Adenine Phosphoribosyltransferase (APRT))
    Binding Specificity
    • 13
    • 10
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 12-40, N-Term
    Reactivity
    • 60
    • 6
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 57
    • 3
    Rabbit
    Clonality
    • 59
    • 1
    Polyclonal
    Conjugate
    • 29
    • 5
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APRT antibody is un-conjugated
    Application
    • 47
    • 28
    • 26
    • 8
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human APRT.
    Clone
    RB20509
    Isotype
    Ig Fraction
  • Application Notes
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Valaperta, Rizzo, Lombardi, Verdelli, Piccoli, Ghiroldi, Creo, Colombo, Valisi, Margiotta, Panella, Costa: "Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation." in: BMC nephrology, Vol. 15, pp. 102, (2014) (PubMed).

  • Target
    APRT (Adenine Phosphoribosyltransferase (APRT))
    Alternative Name
    APRT (APRT Products)
    Synonyms
    Tb07.43M14.200 antibody, Tb07.43M14.180 antibody, C85684 antibody, AMP antibody, APRTD antibody, adenine phosphoribosyltransferase antibody, adenine phosphoribosyl transferase antibody, CND05020 antibody, Tb927.7.1790 antibody, Tb927.7.1780 antibody, Arnit_0941 antibody, Saut_1231 antibody, Fbal_1180 antibody, PH_RS07970 antibody, PF_RS08760 antibody, PAB_RS02560 antibody, Aprt antibody, APRT antibody
    Background
    A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.
    Molecular Weight
    19608
    Gene ID
    353
    NCBI Accession
    NP_000476, NP_001025189
    UniProt
    P07741
    Pathways
    Ribonucleoside Biosynthetic Process
You are here:
Support