IL2 Receptor beta Protein (AA 27-239) (His-Avi Tag)
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- Target See all IL2 Receptor beta (IL2RB) Proteins
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-239
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL2 Receptor beta protein is labelled with His-Avi Tag.
- Purpose
- Human IL-2 R beta/CD122 Protein
- Sequence
- Ala27-Asp239
- Characteristics
- Recombinant Human IL-2 R beta/CD122 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala27-Asp239.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.12 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) protein (Fc Tag)
IL2RB Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 2 Receptor, beta (IL2RB) protein (His-Avi Tag,Biotin)IL2RB Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) protein (His tag)IL2RB Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) protein (His tag,Biotin)IL2RB Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) (Active) protein (Fc Tag)IL2RB Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 2 Receptor, beta (IL2RB) protein (His tag)IL2RB Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 2 Receptor, beta (IL2RB) protein (His tag)IL2RB Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Interleukin 2 Receptor, beta (IL2RB) protein (Fc Tag)IL2RB Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Interleukin 2 Receptor, beta (IL2RB) (AA 266-551) protein (His tag)Crystallography grade IL2RB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 2 Receptor, beta (IL2RB) (AA 27-240) protein (His tag)Crystallography grade IL2RB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- Alternative Name
- IL-2 R beta (IL2RB Products)
- Synonyms
- IL2RB Protein, il-2rb Protein, CD122 Protein, IL15RB Protein, P70-75 Protein, IL2RBC Protein, IL-15Rbeta Protein, IL15Rbeta Protein, Il-2/15Rbeta Protein, Il-2Rbeta Protein, p70 Protein, interleukin 2 receptor subunit beta Protein, interleukin-2 receptor subunit beta Protein, interleukin 2 receptor, beta Protein, interleukin 2 receptor, beta chain Protein, IL2RB Protein, LOC510185 Protein, il2rb Protein, Il2rb Protein
- Background
- IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains, and the intermediate affinity complex comprising heterodimers of the beta and gamma chains.
- Molecular Weight
- 27.5 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_000869
- Pathways
- JAK-STAT Signaling, Growth Factor Binding
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