IL-6 Receptor antibody
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- Target See all IL-6 Receptor (IL6R) Antibodies
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL-6 Receptor antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen Affinity Purification
- Immunogen
- Recombinant Human Interleukin-6 receptor subunit alpha protein
- Isotype
- IgG
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anti-Interleukin 6 Receptor (IL6R) (AA 20-320) antibody
IL6R Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 216-356) antibodyIL6R Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) antibodyIL6R Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 1-468) antibodyIL6R Reactivity: Human WB, FACS Host: Mouse Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 205-347) antibodyIL6R Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 385-462) antibodyIL6R Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (N-Term) antibodyIL6R Reactivity: Human, Mouse WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (N-Term) antibodyIL6R Reactivity: Human, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) antibodyIL6R Reactivity: Human IHC, ELISA, IP, FACS, Func Host: Mouse Monoclonal B-R6 unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 1-468) antibodyIL6R Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000-1:2000 IHC 1:100-1:300
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Alternative Name
- IL6R (IL6R Products)
- Synonyms
- IL6R antibody, il-6ra antibody, CD126 antibody, IL-6R-1 antibody, IL-6RA antibody, IL6Q antibody, IL6RA antibody, IL6RQ antibody, gp80 antibody, IL6R1 antibody, Il6ra antibody, IL-6Ralpha antibody, IL-6R antibody, Il6r antibody, interleukin 6 receptor antibody, interleukin 6 receptor, alpha antibody, IL6R antibody, il6r antibody, Il6r antibody, Il6ra antibody
- Background
- This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
- Molecular Weight
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Observed_MW: 80 kDa
Calculated_MW: 40,51 kDa
- UniProt
- P08887
- Pathways
- JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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