Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PDX1 antibody

PDX1 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 2G12 unconjugated
Catalog No. ABIN969554
  • Target See all PDX1 Antibodies
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    Reactivity
    • 119
    • 45
    • 34
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 133
    • 7
    • 2
    Mouse
    Clonality
    • 126
    • 16
    Monoclonal
    Conjugate
    • 61
    • 13
    • 9
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDX1 antibody is un-conjugated
    Application
    • 90
    • 66
    • 36
    • 20
    • 18
    • 14
    • 14
    • 12
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human PDX1 expressed in E. coli.
    Clone
    2G12
    Isotype
    IgG1
    Top Product
    Discover our top product PDX1 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Ota, Harada, Uehara, Hayama, Ishii: "Aberrant expression of TFF1, TFF2, and PDX1 and their diagnostic value in lobular endocervical glandular hyperplasia." in: American journal of clinical pathology, Vol. 135, Issue 2, pp. 253-61, (2011) (PubMed).

    Mitnala, Pondugala, Guduru, Rabella, Thiyyari, Chivukula, Boddupalli, Hardikar, Reddy: "Reduced expression of PDX-1 is associated with decreased beta cell function in chronic pancreatitis." in: Pancreas, Vol. 39, Issue 6, pp. 856-62, (2010) (PubMed).

  • Target
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    Alternative Name
    PDX1 (PDX1 Products)
    Synonyms
    GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
    Background

    Description: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

    Aliases: GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1

    Molecular Weight
    30.8 kDa
    Gene ID
    3651
    HGNC
    3651
    Pathways
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
You are here:
Support