EIF6 antibody (AA 66-210)
-
- Target See all EIF6 Antibodies
- EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
-
Binding Specificity
- AA 66-210
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This EIF6 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Eukaryotic translation initiation factor 6(EIF6) detection. Tested with WB, IHC-P in Human,Mouse, Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
-
Rabbit IgG polyclonal antibody for Eukaryotic translation initiation factor 6(EIF6) detection. Tested with WB, IHC-P in Human,Mouse, Rat.
Gene Name: eukaryotic translation initiation factor 6
Protein Name: Eukaryotic translation initiation factor 6 - Purification
- Immunogen affinity purified.
- Immunogen
- E.coli-derived human EIF6 recombinant protein (Position: N66-T210). Human EIF6 shares 99.3% amino acid (aa) sequence identity with both mouse and rat EIF6.
- Isotype
- IgG
-
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 1-245) antibody
EIF6 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) antibodyEIF6 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 1-245) antibodyEIF6 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 66-210) antibodyEIF6 Reactivity: Human, Mouse, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 622-848) antibodyEIF6 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 146-245) antibodyEIF6 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (C-Term) antibodyEIF6 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 82-96), (Middle Region) antibodyEIF6 Reactivity: Human, Mouse, Rat WB, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (C-Term) antibodyEIF6 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Sheep, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 145-194) antibodyEIF6 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Sheep, Dog, Guinea Pig, Horse, Chicken, Hamster, Pig, Xenopus laevis, Bat WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
-
- Application Notes
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
- Target
- EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
- Alternative Name
- EIF6 (EIF6 Products)
- Synonyms
- CAB antibody, EIF3A antibody, ITGB4BP antibody, b(2)gcn antibody, eIF-6 antibody, p27(BBP) antibody, p27BBP antibody, 1110004P11 antibody, AA408895 antibody, Itgb4bp antibody, imc-415 antibody, MGC56562 antibody, itgb4bp4 antibody, zgc:56562 antibody, wu:fc28a04 antibody, wu:ft88f05 antibody, itgb4bp antibody, eukaryotic translation initiation factor 6 antibody, Eukaryotic translation initiation factor 6 antibody, eukaryotic translation initiation factor 6 S homeolog antibody, translation initiation factor eIF6 antibody, EIF6 antibody, Eif6 antibody, eif6 antibody, eif-6 antibody, eif6.S antibody, tif6 antibody
- Background
-
EIF6 (Eukaryotic Translation Initiation Factor 6), also called EIF3A or ITGB4BP, is a human gene. By fluorescence in situ hybridization, Sanvito et al. (1998) mapped the ITGB4BP gene to 20q11.2. Ceci et al. (2003) demonstrated that the ribosomal 60S subunit is activated by release of EIF6. In the cytoplasm, EIF6 is bound to free 60S but not to 80S subunits. Furthermore, EIF6 interacts in the cytoplasm with RACK1, a receptor for activated protein kinase C. Gandin et al. (2008) demonstrated that mammalian eIF6 is required for efficient initiation of translation in vivo. Eif6-null mouse embryos were lethal at preimplantation. Heterozygous mice had 50 % reduction of eIF6 levels in all tissues, and showed reduced mass of hepatic and adipose tissues due to a lower number of cells and to impaired G1/S cell cycle progression.
Synonyms: b(2)gcn antibody|B(2)GCN homolog antibody|B4 integrin interactor antibody|Binding protein of beta-4 integrin antibody|CAB antibody| eIF-6 antibody|EIF3A antibody|EIF6 antibody|Eukaryotic translation initiation factor 3A antibody|Eukaryotic translation initiation factor 6 antibody|IF6_HUMAN antibody|ITGB4BP antibody|OK/SW-cl.27 antibody|p27 beta 4 integrin binding protein antibody|p27(BBP) antibody|p27BBP antibody|RP4-614O4.1 antibody - Gene ID
- 3692
- UniProt
- P56537
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
-
