C12orf42 antibody
-
- Target See all C12orf42 products
- C12orf42 (Chromosome 12 Open Reading Frame 42 (C12orf42))
- Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This C12orf42 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human C12ORF42
- Isotype
- IgG
-
anti-Chromosome 12 Open Reading Frame 42 (C12orf42) (AA 110-159) antibody
C12orf42 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Chromosome 12 Open Reading Frame 42 (C12orf42) (N-Term) antibodyC12orf42 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
-
- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- C12orf42 (Chromosome 12 Open Reading Frame 42 (C12orf42))
- Alternative Name
- C12ORF42 (C12orf42 Products)
- Synonyms
- chromosome 12 open reading frame 42 antibody, C12orf42 antibody
- Background
-
Synonyms: Chromosome 12 open reading frame 42, FLJ25323, Hypothetical protein LOC374470, MGC43592, MGC57409, Uncharacterized protein C12orf42, CL042_HUMAN.
Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf42 gene product has been provisionally designated C12orf42 pending further characterization.
- Gene ID
- 374470
-
