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NLRP12 antibody

NLRP12 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032016
  • Target See all NLRP12 Antibodies
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    Reactivity
    • 50
    • 18
    • 14
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 49
    • 3
    • 1
    Rabbit
    Clonality
    • 50
    • 3
    Polyclonal
    Conjugate
    • 19
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP12 antibody is un-conjugated
    Application
    • 36
    • 32
    • 14
    • 13
    • 13
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antigen affinity purified
    Immunogen
    This anti-NLRP12 antibody was produced from rabbits immunized with human NLRP12 recombinant protein.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NLRP12 Primary Antibody
  • Application Notes
    Titration of the anti-NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the anti-NLRP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    Alternative Name
    NLRP12 (NLRP12 Products)
    Synonyms
    Nalp12 antibody, NALP12 antibody, CLR19.3 antibody, FCAS2 antibody, PAN6 antibody, PYPAF7 antibody, RNO antibody, RNO2 antibody, NLR family, pyrin domain containing 12 antibody, NLR family pyrin domain containing 12 antibody, NACHT, LRR and PYD domains-containing protein 3 antibody, Nlrp12 antibody, NLRP12 antibody, LOC100018508 antibody
    Background
    NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes.
    UniProt
    P59046
    Pathways
    Positive Regulation of Endopeptidase Activity, Inflammasome
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