CATSPER4 antibody (AA 306-472)
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- Target See all CATSPER4 Antibodies
- CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
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Binding Specificity
- AA 306-472
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CATSPER4 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)
- Isotype
- IgG
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anti-Cation Channel, Sperm Associated 4 (CATSPER4) antibody
CATSPER4 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
- Alternative Name
- CATSPER4 (CATSPER4 Products)
- Synonyms
- RGD1565213 antibody, 4933412L05 antibody, cation channel, sperm associated 4 antibody, cation channel sperm associated 4 antibody, Catsper4 antibody, CATSPER4 antibody
- Background
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Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .
Aliases: CATSPER4Cation channel sperm-associated protein 4 antibody, CatSper4 antibody
- UniProt
- Q7RTX7
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