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KIR3DL1 antibody (AA 206-340)

KIR3DL1 Reactivity: Human WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 2C3B6 unconjugated
Catalog No. ABIN5611325
  • Target See all KIR3DL1 Antibodies
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    Binding Specificity
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 206-340
    Reactivity
    • 46
    • 18
    • 18
    • 1
    Human
    Host
    • 46
    • 15
    Mouse
    Clonality
    • 46
    • 15
    Monoclonal
    Conjugate
    • 26
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIR3DL1 antibody is un-conjugated
    Application
    • 45
    • 16
    • 14
    • 12
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human CD158E1 (AA: extra 206-340) expressed in E. coli.
    Clone
    2C3B6
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    Alternative Name
    CD158E1 (KIR3DL1 Products)
    Synonyms
    KIR3DL1 antibody, KIR3DL3 antibody, CD158E1 antibody, KIR antibody, KIR3DL1/S1 antibody, NKAT3 antibody, NKB1 antibody, NKB1B antibody, Kirl1 antibody, Kirl2 antibody, Krl1 antibody, killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 antibody, uncharacterized LOC100437736 antibody, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 antibody, KIR3DL1 antibody, LOC100437736 antibody, Kir3dl1 antibody
    Background

    Description: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.

    Aliases: KIR3DL1, KIR, NKB1, NKAT3, NKB1B, NKAT-3, KIR3DL1/S1

    Molecular Weight
    49 kDa
    Gene ID
    3811
    HGNC
    3811
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