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ARF6 antibody (Internal Region)

ARF6 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6260022
  • Target See all ARF6 Antibodies
    ARF6 (ADP-Ribosylation Factor 6 (ARF6))
    Binding Specificity
    • 15
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 56
    • 24
    • 24
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 55
    • 1
    Rabbit
    Clonality
    • 47
    • 9
    Polyclonal
    Conjugate
    • 19
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARF6 antibody is un-conjugated
    Application
    • 18
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    ARF6 Antibody detects endogenous levels of total ARF6.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ARF6, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    ARF6 (ADP-Ribosylation Factor 6 (ARF6))
    Alternative Name
    ARF6 (ARF6 Products)
    Synonyms
    AI788669 antibody, AW496366 antibody, MGC80156 antibody, arf6 antibody, wu:fj46d09 antibody, zgc:77665 antibody, wu:fa98a01 antibody, zgc:172028 antibody, ADP ribosylation factor 6 antibody, ADP-ribosylation factor 6 antibody, ADP ribosylation factor 6 L homeolog antibody, Arf6 protein antibody, ADP-ribosylation factor 6a antibody, ADP-ribosylation factor 6b antibody, ADP ribosylation factor like GTPase 6 antibody, ARF6 antibody, Arf6 antibody, arf6.2.L antibody, arf6 antibody, arf6a antibody, arf6b antibody, ARL6 antibody
    Background

    Description: GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (PubMed:11266366, PubMed:21170023, PubMed:16737952, PubMed:7589240, PubMed:18400762). Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (PubMed:14978216). Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface levels of adherens junction proteins such as CDH1 (By similarity).

    Gene: ARF6

    Molecular Weight
    20kDa
    Gene ID
    382
    UniProt
    P62330
    Pathways
    Steroid Hormone Mediated Signaling Pathway, Regulation of Actin Filament Polymerization, SARS-CoV-2 Protein Interactome
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