Tyrosine Hydroxylase (TH) (N-Term) Peptide
-
- Target See all Tyrosine Hydroxylase (TH) products
- Tyrosine Hydroxylase (TH)
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TH antibody (Catalog #: ARP30889_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- Tyrosine Hydroxylase (TH)
- Synonyms
- DYT14 Peptide, DYT5b Peptide, TYH Peptide, The Peptide, CG10118 Peptide, DH65B Peptide, DTH Peptide, Dmel\\CG10118 Peptide, Pale Peptide, Ple Peptide, TH Peptide, Th Peptide, VII Peptide, dTH1 Peptide, dTH65B Peptide, pale/ple Peptide, th Peptide, dyt14 Peptide, dyt5b Peptide, tyh Peptide, tyrosine hydroxylase Peptide, pale Peptide, tyrosine 3-monooxygenase Peptide, tyrosine hydroxylase S homeolog Peptide, TH Peptide, Th Peptide, ple Peptide, th Peptide, th.S Peptide, LOC100008895 Peptide
- Background
-
The specific function of the protein remains unknown. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: TYH, DYT14, DYT5b
Protein Interaction Partner: CAMK2G,CDK11B,CSNK2A1,MAPK1,MAPK3,MAPKAPK2,PRKACA,RPS6KA5,SNCA,YWHAB,YWHAZ,HR,MAPK1,MAPK3
Protein Size: 528 - Molecular Weight
- 58 kDa
- Gene ID
- 7054
- NCBI Accession
- NM_199292, NP_954986
- UniProt
- P07101
-