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Tyrosine Hydroxylase (TH) (N-Term) Peptide

TH Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985048
  • Target See all Tyrosine Hydroxylase (TH) products
    Tyrosine Hydroxylase (TH)
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TH antibody (Catalog #: ARP30889_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Tyrosine Hydroxylase (TH)
    Synonyms
    DYT14 Peptide, DYT5b Peptide, TYH Peptide, The Peptide, CG10118 Peptide, DH65B Peptide, DTH Peptide, Dmel\\CG10118 Peptide, Pale Peptide, Ple Peptide, TH Peptide, Th Peptide, VII Peptide, dTH1 Peptide, dTH65B Peptide, pale/ple Peptide, th Peptide, dyt14 Peptide, dyt5b Peptide, tyh Peptide, tyrosine hydroxylase Peptide, pale Peptide, tyrosine 3-monooxygenase Peptide, tyrosine hydroxylase S homeolog Peptide, TH Peptide, Th Peptide, ple Peptide, th Peptide, th.S Peptide, LOC100008895 Peptide
    Background
    The specific function of the protein remains unknown. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

    Alias Symbols: TYH, DYT14, DYT5b

    Protein Interaction Partner: CAMK2G,CDK11B,CSNK2A1,MAPK1,MAPK3,MAPKAPK2,PRKACA,RPS6KA5,SNCA,YWHAB,YWHAZ,HR,MAPK1,MAPK3

    Protein Size: 528
    Molecular Weight
    58 kDa
    Gene ID
    7054
    NCBI Accession
    NM_199292, NP_954986
    UniProt
    P07101
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