ILDR2 Protein (AA 21-184) (Fc Tag)
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- Target See all ILDR2 products
- ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-184
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ILDR2 protein is labelled with Fc Tag.
- Purpose
- Human ILDR2 Protein
- Sequence
- Leu21-Met184
- Characteristics
- Recombinant Human ILDR2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Met184.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
- Alternative Name
- ILDR2 (ILDR2 Products)
- Synonyms
- C1orf32 Protein, RP4-782G3.2 Protein, dJ782G3.1 Protein, immunoglobulin like domain containing receptor 2 Protein, ILDR2 Protein
- Background
- Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma and neuronal cells, ILDR2 is primarily located in the endoplasmic reticulum membrane. Livers in knockdown mice were steatotic, with increased hepatic and circulating triglycerides and total cholesterol. Increased circulating VLDL, without reduction in triglyceride clearance suggests an effect of reduced hepatic ILDR2 on hepatic cholesterol clearance.
- Molecular Weight
- 35 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result.
- UniProt
- Q71H61
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