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ILDR2 Protein (AA 21-184) (Fc Tag)

ILDR2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
Catalog No. ABIN7274999
  • Target See all ILDR2 products
    ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-184
    Origin
    • 7
    • 3
    Human
    Source
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ILDR2 protein is labelled with Fc Tag.
    Purpose
    Human ILDR2 Protein
    Sequence
    Leu21-Met184
    Characteristics
    Recombinant Human ILDR2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Met184.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
    Alternative Name
    ILDR2 (ILDR2 Products)
    Synonyms
    C1orf32 Protein, RP4-782G3.2 Protein, dJ782G3.1 Protein, immunoglobulin like domain containing receptor 2 Protein, ILDR2 Protein
    Background
    Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma and neuronal cells, ILDR2 is primarily located in the endoplasmic reticulum membrane. Livers in knockdown mice were steatotic, with increased hepatic and circulating triglycerides and total cholesterol. Increased circulating VLDL, without reduction in triglyceride clearance suggests an effect of reduced hepatic ILDR2 on hepatic cholesterol clearance.
    Molecular Weight
    35 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result.
    UniProt
    Q71H61
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