LAIR2 Protein (AA 22-152) (His-Avi Tag)
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- Target See all LAIR2 Proteins
- LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-152
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LAIR2 protein is labelled with His-Avi Tag.
- Purpose
- Huma LAIR2/CD306 Protein
- Sequence
- Gln22-Pro152
- Characteristics
- Recombinant Huma LAIR2/CD306 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Pro152.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.95 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
- Alternative Name
- LAIR2 (LAIR2 Products)
- Synonyms
- CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein
- Background
- The leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) shows increased expression during pregnancy and its reduced expression is associated with pregnancy complications. Although LAIR2 was expressed in the human placenta villus and decidua in the first trimester of pregnancy, it was not expressed in mouse tissues. Knockdown of LAIR2 markedly improved cell viability and inhibited the invasive ability of HTR8/SVneo cells.
- Molecular Weight
- 17 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result.
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