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LAIR2 Protein (AA 22-152) (His-Avi Tag)

LAIR2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275120
  • Target See all LAIR2 Proteins
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-152
    Origin
    Human
    Source
    • 8
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LAIR2 protein is labelled with His-Avi Tag.
    Purpose
    Huma LAIR2/CD306 Protein
    Sequence
    Gln22-Pro152
    Characteristics
    Recombinant Huma LAIR2/CD306 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Pro152.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.95 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    Alternative Name
    LAIR2 (LAIR2 Products)
    Synonyms
    CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein
    Background
    The leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) shows increased expression during pregnancy and its reduced expression is associated with pregnancy complications. Although LAIR2 was expressed in the human placenta villus and decidua in the first trimester of pregnancy, it was not expressed in mouse tissues. Knockdown of LAIR2 markedly improved cell viability and inhibited the invasive ability of HTR8/SVneo cells.
    Molecular Weight
    17 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result.
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