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Laminin beta 1 antibody

LAMB1 Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7268185
  • Target See all Laminin beta 1 (LAMB1) Antibodies
    Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
    Reactivity
    • 48
    • 31
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 46
    • 5
    Rabbit
    Clonality
    • 39
    • 12
    Monoclonal
    Conjugate
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Laminin beta 1 antibody is un-conjugated
    Application
    • 30
    • 21
    • 18
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purpose
    Laminin beta 1 Rabbit mAb
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human Laminin beta 1
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
    Alternative Name
    LAMB1 (LAMB1 Products)
    Synonyms
    CLM antibody, LIS5 antibody, fc20b05 antibody, gup antibody, lamb1 antibody, sb:cb95 antibody, wu:fc20b05 antibody, Lamb1-1 antibody, LAMB1 antibody, C77966 antibody, C80098 antibody, C81607 antibody, D130003D08Rik antibody, Lamb-1 antibody, laminin subunit beta 1 antibody, laminin, beta 1a antibody, laminin B1 antibody, LAMB1 antibody, lamb1a antibody, Lamb1 antibody, lamb1 antibody
    Background
    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.,CLM, LIS5,Angiogenesis,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Signal Transduction,LAMB1
    Molecular Weight
    198kDa
    Gene ID
    3912
    UniProt
    P07942
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