LAMP1 antibody (AA 301-417)
(5 references)-
- Target See all LAMP1 Antibodies
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
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Binding Specificity
- AA 301-417
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Reactivity
- Human, Mouse, Rat, Monkey
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LAMP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Monkey, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human LAMP-1
- Isotype
- IgG
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anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 49-297) antibody
LAMP1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 Reactivity: Human, Mouse, Non-Human Primate WB, FACS, ICC, IHC (p), IHC (fro) Host: Mouse Monoclonal H4A3 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 Reactivity: Rat WB, IP, IF, ICC Host: Mouse Monoclonal Ly1C6 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 125-154) antibodyLAMP1 Reactivity: Human, Mouse WB, IHC, IF, ELISA Host: Rabbit Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 125-154), (N-Term) antibodyLAMP1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB12577 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (APC)LAMP1 Reactivity: Human, Mouse, Non-Human Primate FACS Host: Mouse Monoclonal H4A3 APC
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 Reactivity: Human, Mouse, Primate WB, FACS, IHC, ICC, IHC (p), IHC (fro) Host: Mouse Monoclonal H4A3 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (FITC)LAMP1 Reactivity: Mouse WB, FACS, IHC, IP, IHC (p), IHC (fro) Host: Rat Monoclonal FITC
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (Biotin)LAMP1 Reactivity: Human FACS, IHC Host: Mouse Monoclonal H4A3 Biotin
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 Reactivity: Mouse WB, FACS, IHC, IP Host: Rat Monoclonal 1D4B unconjugated
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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: "Adipose tissue conditioned media support macrophage lipid-droplet biogenesis by interfering with autophagic flux." in: Biochimica et biophysica acta, Vol. 1862, Issue 9, pp. 1001-1012, (2017) (PubMed).
: "Black Raspberries Enhance Natural Killer Cell Infiltration into the Colon and Suppress the Progression of Colorectal Cancer." in: Frontiers in immunology, Vol. 8, pp. 997, (2017) (PubMed).
: "Niemann-Pick type C2 deficiency impairs autophagy-lysosomal activity, mitochondrial function, and TLR signaling in adipocytes." in: Journal of lipid research, Vol. 57, Issue 9, pp. 1644-58, (2016) (PubMed).
: "Combination of macrophage inflammatory protein 1 alpha with existing therapies to enhance the antitumor effects on murine hepatoma." in: Journal of radiation research, (2014) (PubMed).
: "Porcine reproductive and respiratory syndrome virus induces autophagy to promote virus replication." in: Autophagy, Vol. 8, Issue 10, pp. 1434-47, (2012) (PubMed).
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: "Adipose tissue conditioned media support macrophage lipid-droplet biogenesis by interfering with autophagic flux." in: Biochimica et biophysica acta, Vol. 1862, Issue 9, pp. 1001-1012, (2017) (PubMed).
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- Target
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
- Alternative Name
- LAMP-1 (LAMP1 Products)
- Synonyms
- CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody
- Background
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Synonyms: LAMPA, CD17a, LGP12, Lysosome-associated membrane glycoprotein 1, LAMP-1, Lysosome-associated membrane protein 1, CD17 antigen-like family member A, LAMP1
Background: Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
- Gene ID
- 3916
- UniProt
- P11279
- Pathways
- Autophagy
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