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CCT4 antibody (C-Term)

CCT4 Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775694
  • Target See all CCT4 Antibodies
    CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))
    Binding Specificity
    • 9
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
    Host
    • 43
    Rabbit
    Clonality
    • 43
    Polyclonal
    Conjugate
    • 19
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CCT4 antibody is un-conjugated
    Application
    • 29
    • 17
    • 15
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    AFADAMEVIP STLAENAGLN PISTVTELRN RHAQGEKTAG INVRKGGISN
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against CCT4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CCT4
    Top Product
    Discover our top product CCT4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 539 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tarkar, Loges, Slagle, Francis, Dougherty, Tamayo, Shook, Cantino, Schwartz, Jahnke, Olbrich, Werner, Raidt, Pennekamp, Abouhamed, Hjeij, Köhler, Griese, Li, Lemke, Klena, Liu, Gabriel, Tobita et al.: "DYX1C1 is required for axonemal dynein assembly and ciliary motility. ..." in: Nature genetics, Vol. 45, Issue 9, pp. 995-1003, (2013) (PubMed).

    Machida, Masutani, Kobayashi, Mikami, Nishino, Miyazawa, Imataka: "Reconstitution of the human chaperonin CCT by co-expression of the eight distinct subunits in mammalian cells." in: Protein expression and purification, Vol. 82, Issue 1, pp. 61-9, (2012) (PubMed).

  • Target
    CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))
    Alternative Name
    CCT4 (CCT4 Products)
    Synonyms
    zgc:65789 antibody, zgc:77192 antibody, Cct4 antibody, Dmel\\CG5525 antibody, Tcp-1delta antibody, Tcp1-delta antibody, cct4 antibody, MGC89275 antibody, CCT4 antibody, DKFZp459D1424 antibody, LOC100225853 antibody, cctd antibody, CCT-DELTA antibody, Cctd antibody, SRB antibody, 2610204B21Rik antibody, A45 antibody, C78323 antibody, chaperonin containing TCP1, subunit 4 (delta) antibody, chaperonin containing TCP1 subunit 4 antibody, chaperonin containing TCP1 subunit 4 L homeolog antibody, CG5525 gene product from transcript CG5525-RA antibody, chaperonin containing Tcp1, subunit 4 (delta) antibody, T-complex protein 1 subunit delta antibody, cct4 antibody, CCT4 antibody, cct4.L antibody, CG5525 antibody, Cct4 antibody, cct-4 antibody
    Background
    The CCT (chaperonin containing TCP-1) complex functions as a molecular chaperone in the eukaryotic cytosol. CCT4 interacts with human cyclin E which has been implicated in positive control of the G1/S phase transition.
    Alias Symbols: SRB, Cctd, CCT-DELTA
    Protein Interaction Partner: HUWE1, TP53, FUS, CDC20, NEDD1, TUBG1, LGALS3BP, UBC, STAU1, MDM2, RFWD2, VRK2, PRPF40A, CCT7, USP9X, VARS, CCT3, CCT6A, FBXO6, UBD, FBXW4, CDK9, CDK5, CDK2, CD81, IGSF8, HDAC11, HDAC3, RPS6KA1, ILK, ICAM1, PAN2, VCAM1, PPP5C, PEX14, NOS2, US3, FAM86B2, C
    Protein Size: 539
    Molecular Weight
    58 kDa
    Gene ID
    10575
    NCBI Accession
    NM_006430, NP_006421
    UniProt
    Q53QP9
    Pathways
    Embryonic Body Morphogenesis
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