Sialoadhesin/CD169 antibody
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- Target See all Sialoadhesin/CD169 (SIGLEC1) Antibodies
- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
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Reactivity
- Pig
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Sialoadhesin/CD169 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Porcine CD169, also known as sialoadhesin or Siglec-1, a member of the sialic acid binding immunoglobulin-like lectin (Siglec) family. CD169 was originally identified in mice and identified as the sialic acid dependent Sheep erythrocyte receptor. CD169 has subsequently been identified in rat, human and pig. Was originally raised as part of a panel of anti porcine macrophage monoclonal antibodies raised against isolated porcine alveolar macrophages. Immunohistochemical analysis indicated restriction to macrophage populations mainly in the spleen, lymph nodes, liver and Peyer's patches. Originally described as a non phagocytic intercellular adhesion receptor, work on porcine CD169 indicated that it may play a role as a viral adhesion receptor and as a targeted receptor for the delivery of toxins and antigens. Detects a band of approximately 190 kD in alveolar macrophage extracts under non-reducing conditions.
- Purification
- Protein G purified
- Immunogen
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Porcine alveolar macrophages.
Type of Immunogen: Cells - Clone
- 3B11-11
- Isotype
- IgG1
- Top Product
- Discover our top product SIGLEC1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Target Species of Antibody: Pig
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
- Alternative Name
- SIGLEC1 / CD169 / Sialoadhesin (SIGLEC1 Products)
- Synonyms
- Cd169 antibody, Siglec-1 antibody, Sn antibody, CD169 antibody, SIGLEC-1 antibody, SN antibody, dJ1009E24.1 antibody, SA antibody, SIGLEC1 antibody, p210 antibody, pSn antibody, sialic acid binding Ig like lectin 1 antibody, sialic acid binding Ig-like lectin 1, sialoadhesin antibody, SIGLEC1 antibody, Siglec1 antibody
- Background
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Name/Gene ID: SIGLEC1
Family: Immunoglobulin
Synonyms: SIGLEC1, CD169, CD169 antigen, SIGLEC-1, Sialoadhesin, SN, DJ1009E24.1 - Gene ID
- 6614
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