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Cyclin B2 antibody

CCNB2 Reactivity: Human, Mouse, Rat, Xenopus laevis ELISA, IHC, Coat Host: Mouse Monoclonal X29-2 unconjugated
Catalog No. ABIN6941010
  • Target See all Cyclin B2 (CCNB2) Antibodies
    Cyclin B2 (CCNB2)
    Reactivity
    • 86
    • 30
    • 13
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat, Xenopus laevis
    Host
    • 96
    • 4
    • 3
    Mouse
    Clonality
    • 89
    • 14
    Monoclonal
    Conjugate
    • 43
    • 10
    • 10
    • 9
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cyclin B2 antibody is un-conjugated
    Application
    • 55
    • 49
    • 42
    • 14
    • 13
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Coating (Coat)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant full-length Xenopus laevis Cyclin B2 protein
    Clone
    X29-2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CCNB2 Primary Antibody
  • Application Notes

    Positive Control: HeLa cells. Human cervical tissue (IHC).

    Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    Cyclin B2 (CCNB2)
    Alternative Name
    CCNB2 (CCNB2 Products)
    Synonyms
    HsT17299 antibody, CycB2 antibody, sb:cb303 antibody, cycB2 antibody, LOC100136691 antibody, C-B2 antibody, cyclinb2 antibody, hst17299 antibody, LOC100282653 antibody, cyclin B2 antibody, cyclin B2 S homeolog antibody, CCNB2 antibody, Ccnb2 antibody, ccnb2 antibody, LOC100136691 antibody, LOC100282653 antibody, ccnb2.S antibody
    Background
    In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc1). The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/ cyclin B enzyme, and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions.
    Molecular Weight
    51kDa
    Gene ID
    9133
    UniProt
    O95067
    Pathways
    Cell Division Cycle, M Phase
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