LIMS1 antibody
(2 references)-
- Target See all LIMS1 Antibodies
- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This LIMS1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human PINCH expressed in E. coli.
- Clone
- 5G7
- Isotype
- IgG1
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anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (AA 1-325) antibody
LIMS1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 Reactivity: Human, Mouse WB, IF Host: Rabbit Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (AA 68-303) antibodyLIMS1 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (AA 28-54) antibodyLIMS1 Reactivity: Human WB Host: Rabbit Polyclonal RB38877 unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 Reactivity: Human, Mouse, Rat WB, IF, IC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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: "Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5836-44, (2009) (PubMed).
: "The structural basis of integrin-linked kinase-PINCH interactions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 52, pp. 20677-82, (2008) (PubMed).
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: "Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5836-44, (2009) (PubMed).
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- Target
- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
- Alternative Name
- PINCH (LIMS1 Products)
- Synonyms
- PINCH antibody, PINCH-1 antibody, PINCH1 antibody, Pinch1 antibody, RGD1560732 antibody, LIMS3 antibody, LIMS3L antibody, 2310016J22Rik antibody, 4921524A02Rik antibody, AI507642 antibody, AU021743 antibody, AW551584 antibody, C430041B13Rik antibody, Lims1l antibody, LIM zinc finger domain containing 1 antibody, LIM and senescent cell antigen-like domains 1 antibody, LIMS1 antibody, Lims1 antibody
- Background
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Description: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Aliases: PINCH, PINCH1, PINCH-1, LIMS1
- Molecular Weight
- 37 kDa
- Gene ID
- 3987
- HGNC
- 3987
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