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Lipase A antibody (Center)

LIPA Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854960
  • Target See all Lipase A (LIPA) Antibodies
    Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
    Binding Specificity
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 28
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 22
    • 6
    • 1
    Rabbit
    Clonality
    • 24
    • 6
    Polyclonal
    Conjugate
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lipase A antibody is un-conjugated
    Application
    • 24
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Pig (Porcine)
    Cross-Reactivity (Details)
    Pig (84 %)
    Characteristics
    Rabbit Polyclonal antibody to LAL (lipase A, lysosomal acid, cholesterol esterase)
    LAL antibody [N3C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human LAL. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    Comment

    Positive Control: A549 , H1299 , mouse liver

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Rivera-Serrano, González-López, Das, Lemon: "Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses." in: eLife, Vol. 8, (2019) (PubMed).

  • Target
    Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
    Alternative Name
    LAL (LIPA Products)
    Synonyms
    cesd antibody, lal antibody, LIPA antibody, CESD antibody, LAL antibody, Chole antibody, Chole2 antibody, Lip1 antibody, AA960673 antibody, Lal antibody, Lip-1 antibody, lipase A, lysosomal acid type antibody, lipase A, lysosomal acid, cholesterol esterase antibody, lipase A, lysosomal acid, cholesterol esterase L homeolog antibody, lysosomal acid lipase A antibody, LIPA antibody, lipa antibody, lipa.L antibody, Lipa antibody
    Background
    This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Lysosome
    Molecular Weight
    45 kDa
    Gene ID
    3988
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