VWA5A antibody
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- Target See all VWA5A Antibodies
- VWA5A (Von Willebrand Factor A Domain Containing 5A (VWA5A))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VWA5A antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human VWA5A
- Isotype
- IgG
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anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (AA 1-786) antibody
VWA5A Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (AA 1-415) antibodyVWA5A Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (AA 332-415) antibodyVWA5A Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (AA 179-228) antibodyVWA5A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) antibodyVWA5A Reactivity: Human, Mouse, Monkey WB, IF, IHC, FACS, IHC (p) Host: Mouse Monoclonal 3A3 unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (Center) antibodyVWA5A Reactivity: Human, Mouse, Rat, Monkey WB, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (N-Term) antibodyVWA5A Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- VWA5A (Von Willebrand Factor A Domain Containing 5A (VWA5A))
- Alternative Name
- VWA5A (VWA5A Products)
- Background
- VWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80 % of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin, alpha-catenin, and p53, resulting in a decrease of malignant activity in cells with ectopic expression of VWA5A.
- Molecular Weight
- 86 kDa
- UniProt
- O00534
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