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LRP6 antibody (AA 1198-1370)

LRP6 Reactivity: Human WB, IHC, ELISA, FACS, ICC, Neut Host: Mouse Monoclonal 1A3F5 unconjugated
Catalog No. ABIN7193277
  • Target See all LRP6 Antibodies
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    Binding Specificity
    • 17
    • 16
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1198-1370
    Reactivity
    • 57
    • 37
    • 18
    • 2
    • 2
    Human
    Host
    • 55
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 57
    • 2
    Monoclonal
    Conjugate
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This LRP6 antibody is un-conjugated
    Application
    • 53
    • 26
    • 26
    • 21
    • 16
    • 16
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human LRP6 (AA: extra 1198-1370) expressed in E. coli.
    Clone
    1A3F5
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    Alternative Name
    LRP6 (LRP6 Products)
    Synonyms
    lrp6-A antibody, Xlrp6 antibody, adcad2 antibody, lrp6 antibody, LRP6 antibody, ADCAD2 antibody, C030016K15Rik antibody, Cd antibody, Gw antibody, LDL receptor related protein 6 antibody, LDL receptor related protein 6 L homeolog antibody, LDL receptor related protein 6 S homeolog antibody, low density lipoprotein receptor-related protein 6 antibody, low-density lipoprotein receptor-related protein 6 antibody, LRP6 antibody, lrp6.L antibody, lrp6.S antibody, lrp6 antibody, Lrp6 antibody, LOC590395 antibody
    Background

    Description: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

    Aliases: ADCAD2, STHAG7

    Molecular Weight
    180 kDa
    Gene ID
    4040
    Pathways
    WNT Signaling, Tube Formation
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