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MGMT antibody

MGMT Reactivity: Human WB, IHC, FACS, IHC (p) Host: Mouse Monoclonal MT 23-2 unconjugated
Catalog No. ABIN534106
  • Target See all MGMT Antibodies
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Reactivity
    • 72
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 69
    • 10
    Mouse
    Clonality
    • 62
    • 17
    Monoclonal
    Conjugate
    • 44
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MGMT antibody is un-conjugated
    Application
    • 54
    • 33
    • 22
    • 21
    • 13
    • 13
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Mouse monoclonal antibody raised against recombinant MGMT.
    Specificity
    This antibody is specific to MGMT.
    Cross-Reactivity
    Human
    Immunogen
    Recombinant protein corresponding to human MGMT.
    Clone
    MT 23-2
    Isotype
    IgG2b
    Top Product
    Discover our top product MGMT Primary Antibody
  • Application Notes
    Flow Cytometry (1:1000)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1000)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In buffer containing 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C or -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Cai, Xu, Cooper, Ferkowicz, Hartwell, Pollok, Kelley: "Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents." in: Cancer research, Vol. 65, Issue 8, pp. 3319-27, (2005) (PubMed).

    Zuo, Ai, Ratliff, Suen, Hanna, Brent, Fan: "O6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 13, Issue 6, pp. 967-75, (2004) (PubMed).

    Roth, Xu, Luo, Kelley: "Human-yeast chimeric repair protein protects mammalian cells against alkylating agents: enhancement of MGMT protection." in: Cancer gene therapy, Vol. 10, Issue 8, pp. 603-10, (2003) (PubMed).

  • Target
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Alternative Name
    MGMT (MGMT Products)
    Synonyms
    AGT antibody, AI267024 antibody, Agat antibody, O-6-methylguanine-DNA methyltransferase antibody, MGMT antibody, Mgmt antibody
    Gene ID
    4255
    Pathways
    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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