Mre11 antibody (AA 1-205)
(3 references)-
- Target See all Mre11 (MRE11A) Antibodies
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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Binding Specificity
- AA 1-205
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Mre11 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Sequence
- MSTADALDDE NTFKILVATD IHLGFMEKDA VRGNDTFVTL DEILRLAQEN EVDFILLGGD LFHENKPSRK TLHTCLELLR KYCMGDRPVQ FEILSDQSVN FGFSKFPWVN YQDGNLNISI PVFSIHGNHD DPTGADALCA LDILSCAGFV NHFGRSMSVE KIDISPVLLQ KGSTKIALYG LGSIPDERLY RMFVNKKVTM LRPKE
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human MRE11 (NP_005581.2).
- Isotype
- IgG
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anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) antibody
MRE11A Reactivity: Human, Rat, Mouse, Chicken, Hamster WB, IHC, IF, IP, ICC, ChIP, FACS Host: Rabbit Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 375-609) antibodyMRE11A Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibodyMRE11A Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibodyMRE11A Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 451-550) antibodyMRE11A Reactivity: Rat WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (C-Term) antibodyMRE11A Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Internal Region) antibodyMRE11A Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 2-239) antibodyMRE11A Reactivity: Human, Rat, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (C-Term) antibodyMRE11A Reactivity: Human, Rat, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Ser916) antibodyMRE11A Reactivity: Human, Rat, Mouse, Monkey WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
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: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).
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- Target
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
- Alternative Name
- MRE11 (MRE11A Products)
- Synonyms
- wu:faa63d12 antibody, zgc:64018 antibody, Mre11 antibody, Mre11b antibody, ATLD antibody, HNGS1 antibody, MRE11 antibody, MRE11B antibody, MRE11 homolog A, double strand break repair nuclease antibody, MRE11 homolog, double strand break repair nuclease antibody, MRE11A homolog A, double strand break repair nuclease antibody, mre11a antibody, MRE11 antibody, Mre11a antibody
- Background
- This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.,MRE11,ATLD,HNGS1,MRE11A,MRE11B,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,Immunology & Inflammation,MRE11
- Molecular Weight
- 77 kDa/80 kDa/81 kDa
- Gene ID
- 4361
- UniProt
- P49959
- Pathways
- DNA Damage Repair
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