NR4A2 antibody (N-Term)
(1 reference)-
- Target See all NR4A2 Antibodies
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR4A2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- MPCVQAQYGS SPQGASPASQ SYSYHSSGEY SSDFLTPEFV KFSMDLTNTE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against NR4A2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR4A2
- Top Product
- Discover our top product NR4A2 Primary Antibody
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anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 71-170) antibody
NR4A2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4A6 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 164-197) antibodyNR4A2 Reactivity: Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal RB52431 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42), (N-Term) antibodyNR4A2 Reactivity: Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal RB7385 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 13-42) antibodyNR4A2 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibodyNR4A2 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibodyNR4A2 Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit, Cow, Pig, Monkey, Xenopus laevis, Bat, Chicken, Hamster WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 1-335) antibodyNR4A2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) antibodyNR4A2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) antibodyMicroarray verified NR4A2 Reactivity: Human, Mouse IHC Host: Mouse Monoclonal MAB773479 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (AA 1-598) antibodyNR4A2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 598 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Epigenetic reprogramming of cortical neurons through alteration of dopaminergic circuits." in: Molecular psychiatry, Vol. 19, Issue 11, pp. 1193-200, (2014) (PubMed).
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: "Epigenetic reprogramming of cortical neurons through alteration of dopaminergic circuits." in: Molecular psychiatry, Vol. 19, Issue 11, pp. 1193-200, (2014) (PubMed).
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- Target
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
- Alternative Name
- NR4A2 (NR4A2 Products)
- Synonyms
- nr41/42/43 antibody, Nr4a2 antibody, nurr1 antibody, not antibody, rnr1 antibody, hzf-3 antibody, tinur antibody, NGFI-B antibody, HZF-3 antibody, NOT antibody, NURR1 antibody, RNR1 antibody, TINUR antibody, Nurr1 antibody, RNR-1 antibody, TINOR antibody, ngf1b antibody, nr4a2 antibody, zgc:92696 antibody, nuclear receptor subfamily 4 group A member 2 antibody, nuclear receptor antibody, nuclear receptor subfamily 4, group A, member 2 antibody, nuclear receptor subfamily 4, group A, member 2b antibody, NR4A2 antibody, nr41/42/43 antibody, nr4a2 antibody, Nr4a2 antibody, nr4a2b antibody
- Background
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NR4A2 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The protein may act as a transcription factor. Mutations in NR4A2 gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of NR4A2 gene may be associated with rheumatoid arthritis.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HZF-3, NOT, NURR1, RNR1, TINUR
Protein Interaction Partner: CDKN2D, TCEAL5, BAZ1B, ELAVL1, COPS5, RXRB, RXRA, RUNX1, SMARCA4, SMARCA2, SIN3A, NCOR2, SFPQ, PIAS4, RPS6KA1, CDKN1C, RARB, RARA, CREB1,
Protein Size: 598 - Molecular Weight
- 66 kDa
- Gene ID
- 4929
- NCBI Accession
- NM_006186, NP_006177
- UniProt
- P43354
- Pathways
- Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway
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