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POU1F1 antibody (C-Term)

POU1F1 Reactivity: Human, Mouse, Rat, Dog, Cow, Goat, Horse, Rabbit, Sheep, Guinea Pig, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777285
  • Target See all POU1F1 Antibodies
    POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
    Binding Specificity
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 9
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Goat, Horse, Rabbit, Sheep, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 9
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 9
    This POU1F1 antibody is un-conjugated
    Application
    • 7
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    QEIMRMAEEL NLEKEVVRVW FCNRRQREKR VKTSLNQSLF SISKEHLECR
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against POU1F1. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human POU1F1
    Top Product
    Discover our top product POU1F1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 291 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tennant, Gottlieb: "HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression." in: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 8, pp. 839-49, (2010) (PubMed).

  • Target
    POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
    Alternative Name
    POU1F1 (POU1F1 Products)
    Synonyms
    CPHD1 antibody, GHF-1 antibody, PIT1 antibody, POU1F1a antibody, Pit-1 antibody, Hmp1 antibody, Pit1 antibody, Pit1-rs1 antibody, dw antibody, dwarf antibody, GHF1 antibody, GHF1A antibody, PIT1Z antibody, PIT-1 antibody, Pit-1* antibody, pit1 antibody, pit-1 antibody, POU class 1 homeobox 1 antibody, POU domain, class 1, transcription factor 1 antibody, POU1F1 antibody, Pou1f1 antibody, pou1f1 antibody
    Background
    PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
    Alias Symbols: PIT1, CPHD1, GHF-1, Pit-1, POU1F1a
    Protein Interaction Partner: CEBPD, NCOR1, CREBBP, MED1, GATA2, NR1I3, NR1I2, PITX1, JUN, ETS1, NR3C1, VDR, PPARG, PPARA,
    Protein Size: 291
    Molecular Weight
    33 kDa
    Gene ID
    5449
    NCBI Accession
    NM_000306, NP_000297
    UniProt
    P28069
    Pathways
    Regulation of Carbohydrate Metabolic Process
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