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NUDT1 antibody (AA 49-82)

NUDT1 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7142858
  • Target See all NUDT1 Antibodies
    NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))
    Binding Specificity
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 49-82
    Reactivity
    • 28
    • 13
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 25
    • 3
    Rabbit
    Clonality
    • 25
    • 3
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUDT1 antibody is un-conjugated
    Application
    • 17
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human 7,8-dihydro-8-oxoguanine triphosphatase protein (49-82AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))
    Alternative Name
    NUDT1 (NUDT1 Products)
    Synonyms
    mutT antibody, nudT1 antibody, MTH1 antibody, Mth1 antibody, 7,8-dihydro-8-oxoguanine triphosphatase antibody, nudix hydrolase 1 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 1 antibody, mth1 antibody, Tsp_07498 antibody, nudt1 antibody, 8odp antibody, NUDT1 antibody, Nudt1 antibody
    Background

    Background: Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.

    Aliases: 2-hydroxy-dATP diphosphatase antibody, 7 8 dihydro 8 oxoguanine triphosphatase antibody, 7 antibody, 8 oxo 7 8 dihydrodeoxyguanosine triphosphatase antibody, 8 oxo 7 8 dihydroguanosine triphosphatase antibody, 8 oxo dGTPase antibody, 8-dihydro-8-oxoguanine triphosphatase antibody, 8-oxo-dGTPase antibody, 8ODP_HUMAN antibody, MTH 1 antibody, MTH1 antibody, MutT human homolog 1 antibody, Nucleoside diphosphate linked moiety X motif 1 antibody, Nucleoside diphosphate linked moiety X type motif 1 antibody, Nucleoside diphosphate-linked moiety X motif 1 antibody, Nudix (nucleoside diphosphate linked moiety X) type motif 1 antibody, Nudix hydrolase 1 antibody, Nudix motif 1 antibody, Nudix type motif 1 antibody, NUDT 1 antibody, Nudt1 antibody

    UniProt
    P36639
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