ABL1 antibody (AA 490-590)
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- Target See all ABL1 Antibodies
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
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Binding Specificity
- AA 490-590
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ABL1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- HQAFETMFQE SSISDEVEKE LGKQGVRGAV STLLQAPELP TKTRTSRRAA EHRDTTDVPE MPHSKGQGES DPLDHEPAVS PLLPRKERGP PEGGLNEDER L
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 490-590 of human ABL1 (NP_005148.2).
- Isotype
- IgG
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anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr245) antibody
ABL1 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr251) antibodyABL1 Reactivity: Human WB, IF, IHC (p), DB Host: Rabbit Polyclonal RB7351 unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr393), (pTyr412) antibodyABL1 Reactivity: Human, Mouse, Monkey WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr412) antibodyABL1 Reactivity: Human, Mouse, Monkey WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) antibodyABL1 Reactivity: Human, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr412) antibodyABL1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (AA 741-769) antibodyABL1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr204) antibodyABL1 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr245) antibodyABL1 Reactivity: Human, Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal RB7349 unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr134) antibodyABL1 Reactivity: Human IHC (p), DB Host: Rabbit Polyclonal RB7343 unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
- Alternative Name
- ABL1 (ABL1 Products)
- Synonyms
- ABL antibody, JTK7 antibody, bcr/abl antibody, c-ABL antibody, p150 antibody, v-abl antibody, AI325092 antibody, Abl antibody, E430008G22Rik antibody, c-Abl antibody, ABL proto-oncogene 1, non-receptor tyrosine kinase antibody, c-abl oncogene 1, non-receptor tyrosine kinase antibody, Tyrosine-protein kinase abl-1 antibody, ABL1 antibody, Abl1 antibody, abl-1 antibody, abl1 antibody
- Background
- This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9,22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR, MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.,ABL,JTK7,p150,c-ABL,v-abl,CHDSKM,c-ABL1,ABL1,c-Abl,bcr/abl,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,G1/S Checkpoint,G2/M DNA Damage Checkpoint,Microtubules,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,ABL1
- Molecular Weight
- 122 kDa/124 kDa
- Gene ID
- 25
- UniProt
- P00519
- Pathways
- Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
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