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MUC2 antibody (C-Term)

MUC2 Reactivity: Human IHC, WB, IF, IHC (p), ICC, IHC (fro), FISH Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854828
  • Target See all MUC2 Antibodies
    MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
    Binding Specificity
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 62
    • 15
    • 11
    • 2
    Human
    Host
    • 53
    • 22
    • 1
    Rabbit
    Clonality
    • 42
    • 34
    Polyclonal
    Conjugate
    • 35
    • 12
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MUC2 antibody is un-conjugated
    Application
    • 31
    • 30
    • 17
    • 16
    • 14
    • 10
    • 9
    • 8
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Fluorescence in situ hybridization (FISH)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to MUC2 (mucin 2, oligomeric mucus/gel-forming)
    MUC2 antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MUC2. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Toubai, Fujiwara, Rossi, Riwes, Tamaki, Zajac, Liu, Mathew, Byun, Oravecz-Wilson, Matsuda, Sun, Peltier, Wu, Chen, Seregin, Henig, Kim, Brabbs, Pennathur, Chen, Reddy: "Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition." in: Nature microbiology, Vol. 4, Issue 5, pp. 800-812, (2019) (PubMed).

  • Target
    MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
    Alternative Name
    mucin 2, oligomeric mucus/gel-forming (MUC2 Products)
    Background
    This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80 % is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

    Cellular Localization: Secreted
    Molecular Weight
    540 kDa
    Gene ID
    4583
    UniProt
    Q02817
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