MYBL2 antibody (N-Term)
(1 reference)-
- Target See all MYBL2 Antibodies
- MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
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Binding Specificity
- AA 1-17, N-Term
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MYBL2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Purpose
- Rabbit IgG polyclonal antibody for Myb-related protein B(MYBL2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
- Sequence
- MSRRTRCEDL DELHYQD
- Cross-Reactivity (Details)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Characteristics
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Rabbit IgG polyclonal antibody for Myb-related protein B(MYBL2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: v-myb myeloblastosis viral oncogene homolog(avian)-like 2
Protein Name: Myb-related protein B - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human B MyB(1-17aa MSRRTRCEDLDELHYQD), identical to the related mouse sequence and different from the related rat sequence by two amino acids.
- Isotype
- IgG
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anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (N-Term) antibody
MYBL2 Reactivity: Human, Rat, Mouse WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 601-700) antibodyMYBL2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1C7 unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 1-700) antibodyMYBL2 Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (N-Term) antibodyMYBL2 Reactivity: Human, Rat, Dog, Cow, Horse, Monkey, Guinea Pig, Chicken, Zebrafish (Danio rerio) WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 540-571) antibodyMYBL2 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB53927 unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 188-366) antibodyMYBL2 Reactivity: Human ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 101-200) antibodyMYBL2 Reactivity: Human, Rat, Mouse WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 601-700) antibodyMYBL2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (N-Term) antibodyMYBL2 Reactivity: Human, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 245-278) antibodyMYBL2 Reactivity: Human WB Host: Rabbit Polyclonal RB54346 unconjugated
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for MYBL2 is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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: "Molecular mechanism of G1 arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells." in: Cancer cell international, Vol. 17, pp. 35, (2017) (PubMed).
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: "Molecular mechanism of G1 arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells." in: Cancer cell international, Vol. 17, pp. 35, (2017) (PubMed).
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- Target
- MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
- Alternative Name
- MYBL2 (MYBL2 Products)
- Synonyms
- MYBL2 antibody, bmyb antibody, b-myb antibody, B-Myb antibody, Bmyb antibody, B-MYB antibody, BMYB antibody, myb1 antibody, MYB proto-oncogene like 2 antibody, v-myb avian myeloblastosis viral oncogene homolog-like 2b antibody, myeloblastosis oncogene-like 2 antibody, MYB proto-oncogene like 2 S homeolog antibody, MYBL2 antibody, mybl2 antibody, mybl2b antibody, Mybl2 antibody, mybl2.S antibody
- Background
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MYBL2(V-MYB avian myeloblastosis viral oncogene homolog-like 2), also called MYB-RELATED GENE BMYB, is a protein that in humans is encoded by the MYBL2 gene. The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. Barletta et al.(1991) assigned the MYBL2 gene to chromosome Xq13. However, Noben-Trauth et al.(1996) demonstrated that this assignment was an error. Using mouse Mybl2 cDNA clones as probes, they assigned Mybl2 in an interspecific backcross panel to distal mouse chromosome 2. Using human cDNA probes in combination with fluorescence in situ hybridization analysis, they localized MYBL2 to chromosome 20q13.1, a region that is commonly deleted in myeloid disorders and shows high homology of synteny to mouse chromosome 2. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
Synonyms: B-Myb antibody|BMyB antibody|MGC15600 antibody|MYB L2 antibody|Myb related protein B antibody|Myb-like protein 2 antibody|Myb-related protein B antibody|MybB antibody|MYBB_HUMAN antibody|MYBL 2 antibody|MYBL2 antibody|v myb avian myeloblastosis viral oncogene homolog like 2 antibody|v myb myeloblastosis viral oncogene homolog(avian) like 2 antibody|v myb myeloblastosis viral oncogene homolog like 2 antibody - UniProt
- P10244
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding
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