MYO9B antibody (N-Term)
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- Target See all MYO9B Antibodies
- MYO9B (Myosin IXB (MYO9B))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MYO9B antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- MYO9B Antibody detects endogenous levels of total MYO9B.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MYO9B, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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anti-Myosin IXB (MYO9B) (N-Term) antibody
MYO9B Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Myosin IXB (MYO9B) (Internal Region) antibodyVerified MYO9B Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MYO9B (Myosin IXB (MYO9B))
- Alternative Name
- MYO9B (MYO9B Products)
- Synonyms
- CELIAC4 antibody, MYR5 antibody, MYO9B antibody, fb53f01 antibody, wu:fb53f01 antibody, wu:fc47c07 antibody, si:dkeyp-66d1.8 antibody, myosin IXB antibody, myosin IXb antibody, unconventional myosin-IXb antibody, MYO9B antibody, Myo9b antibody, myo9b antibody, LOC100450445 antibody
- Background
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Description: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions (PubMed:9490638). Also acts as a GTPase activator for RHOA (PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257).
Gene: MYO9B
- Molecular Weight
- 250 kDa
- Gene ID
- 4650
- UniProt
- Q13459
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