Norrie Disease (Pseudoglioma) antibody
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- Target See all Norrie Disease (Pseudoglioma) (NDP) Antibodies
- Norrie Disease (Pseudoglioma) (NDP)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Norrie Disease (Pseudoglioma) antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- NDP Antibody detects endogenous levels of total NDP
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human NDP
- Isotype
- IgG
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anti-Norrie Disease (Pseudoglioma) (NDP) (AA 25-133) antibody
NDP Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (AA 25-133) antibodyNDP Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (AA 1-133) antibodyNDP Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) antibodyNDP Reactivity: Mouse WB Host: Rabbit Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (Middle Region) antibodyNDP Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (N-Term) antibodyNDP Reactivity: Human WB, IF, EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- Norrie Disease (Pseudoglioma) (NDP)
- Alternative Name
- NDP (NDP Products)
- Synonyms
- EVR2 antibody, FEVR antibody, ND antibody, evr2 antibody, fevr antibody, xnorrin antibody, Ndph antibody, RGD1563968 antibody, NDP, norrin cystine knot growth factor antibody, Norrie disease (pseudoglioma) L homeolog antibody, Norrie disease (pseudoglioma) (human) antibody, NDP antibody, ndp.L antibody, Ndp antibody
- Background
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Description: Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.
Gene: NDP
- Molecular Weight
- 15kDa
- Gene ID
- 4693
- UniProt
- Q00604
- Pathways
- Sensory Perception of Sound
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